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M9490053.TXT
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1994-09-03
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Document 0053
DOCN M9490053
TI [Specificity of surface antigen and function of BAL T cells]
DT 9411
AU Yamasaki H; Furuie H; Ando M; First Department of Internal Medicine,
Kumamoto University School; of Medicine.
SO Nippon Rinsho. 1994 Jun;52(6):1462-6. Unique Identifier : AIDSLINE
MED/94322467
AB To elucidate the pathogenesis of sarcoidosis, we mainly investigated the
surface molecules including adhesion molecules on BAL T cells and the
functions of BAL T cells such cytokine production, [Ca2+] mobilization,
PKC expression. Results are following. Adhesion molecules were
up-regulated on BAL T cells compared with peripheral T cells, but
cytokine production was decreased via TcR stimulation through [Ca2+]
mobilization was occurred. PKC isozyme alpha expression was decreased
compared with peripheral blood T cells.
DE Antigens, Surface/*PHYSIOLOGY Bronchoalveolar Lavage Fluid/*CYTOLOGY
Calcium/METABOLISM Cell Adhesion Molecules/METABOLISM
Cytokines/METABOLISM CD4-CD8 Ratio English Abstract Human Protein
Kinase C/METABOLISM Sarcoidosis/IMMUNOLOGY T-Lymphocytes/*IMMUNOLOGY
JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).